Of Russian origin but born in Italy and of Argentinean and German nationality, Ana Chumachenco started to play the violin at the age of four under the supervision of her father, a disciple of Leopold Auer, and later with Ljerko Spiller in Buenos Aires.

After achieving a remarkable career in her early years, she returned to Europe at the age of 17 to continue her studies. A year later she was awarded the gold medal at the Carl Flesch competition in London, and a few years later the silver medal at the Queen Elizabeth Competition in Brussels. Her musical mentors in those years were Joseph Szigeti, Sandor Vegh and Yehudi Menuhin.

Besides her appearances in recitals as a soloist with major orchestras, Ana Chumachenco has dedicated much of her time to chamber music, especially in a string trio with her husband and violist, Oscar Lysy, and cellist Walter Notas, with whom, under the name of the Munich String Trio, she has performed for over 20 years.

In 1978, Ana Chumachenco received a guest professorship at the Menuhin Academy in Gstaad, which she held for ten years. Since then she has held a professorship at the University of Music and Performing Arts in Munich and regularly gives masterclasses. 

From her educational work, several international award winners have emerged, and many of their students are now internationally known soloists. Among the most prominent graduates of their class are Julia Fischer, Arabella Steinbacher or Veronika Eberle.

Ana Chumachenco is periodically invited to take part as a juror in major violin competitions, such as the Queen Elisabeth International Music Competition of Belgium, the International Jean Sibelius Violin Competition in Helsinki, and others.